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Dependency This post demonstrate the following:
Quantile Normalization implemented in R package preprocessCore. Inverse-Normal-Transform implemented in RNOmni source("http://www.bioconductor.org/biocLite.R") biocLite("preprocessCore") install.packages("RNOmni") library(preprocessCore) library(RNOmni) General Princinples Quantile Normalization Simplest way to put it: Quantile normalization is a technique for making different distributions have the same statistical property by “aligning”" their quantiles.
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summary(cars) ## speed dist ## Min. : 4.0 Min. : 2.00 ## 1st Qu.:12.0 1st Qu.: 26.00 ## Median :15.0 Median : 36.00 ## Mean :15.4 Mean : 42.98 ## 3rd Qu.