statistics

Quantile Normalization and Inverse Normal Transform

[image] # Caption (optional) caption = “Image credit: Unsplash” # Focal point (optional) # Options: Smart, Center, TopLeft, Top, TopRight, Left, Right, BottomLeft, Bottom, BottomRight focal_point = “” Dependency This post demonstrate the following: Quantile Normalization implemented in R package preprocessCore. Inverse-Normal-Transform implemented in RNOmni source("http://www.bioconductor.org/biocLite.R") biocLite("preprocessCore") install.packages("RNOmni") library(preprocessCore) library(RNOmni) General Princinples Quantile Normalization Simplest way to put it: Quantile normalization is a technique for making different distributions have the same statistical property by “aligning”" their quantiles.